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Biomarkers of Neurodegenerative Disorders: Current Progress and Future Directions
Rawan Tarawneh
Page: 637
Format: pdf, ePub, mobi, fb2
ISBN: 9783031808487
Publisher: Springer Nature Switzerland

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This book presents state-of-the-art knowledge regarding fluid and imaging biomarkers of neurodegenerative disorders, including Alzheimer disease and related dementias (ADRD). A cadre of the top experts in the field discuss the diagnostic and prognostic value of established and emerging biomarkers in ADRD, their ability to track or monitor disease progression or predict cognitive outcomes, and their potential as novel therapeutic targets. Biomarkers are discussed both in the context of specific disease mechanisms, including amyloid, tau, and synuclein pathologies, endothelial, vascular, neuronal, and synaptic injury, and glial reactivity as well as a wide spectrum of neurodegenerative disorders that encompass various pathologies. Multi-omics approaches in ADRD biomarker and drug target discovery including proteomics, genomics, and transcriptomics are covered. Importantly, the authors highlight the need to integrate biomarkers into various stages of ADRD drug development to accelerate drug discovery and approval. The book provides in-depth insight regarding significant progress in ADRD biomarker research over the last decade, addresses potential challenges in the translation of ADRD biomarkers into the clinic, and proposes important directions for future research.

Fluid biomarkers in frontotemporal dementia: past, present and future
In turn, alongside the development of novel methodologies for measuring proteins and other molecules in biological fluids, the last 10 years have seen a huge .
Diagnostic Tools: Fluid Biomarkers for Alzheimer's Disease
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Biomarkers of Neurodegenerative Disorders: Current Progress and .
This book presents state-of-the-art knowledge regarding fluid and imaging biomarkers of neurodegenerative disorders, including Alzheimer disease and related .
Recent progress in biomarkers for neurodegenerative disorders
Here we summarise current knowledge about biological markers available for early Alzheimer Disease detection. In fact delineating disease .
[PDF] Rawan Tarawneh Editor - Biomarkers of Neurodegenerative Disorders
This book consists of 21 chapters and an epilogue, which explore the current progress and future directions in the use of blood, CSF, and .
Editorial: Trends in biomarkers for neurodegenerative diseases
Major advancements have been made in the development of cerebrospinal fluid (CSF), imaging, and blood-based biomarkers for several neurodegenerative diseases ( .
Biomarkers of Neurodegenerative Disorders - eBooks.com
The book provides in-depth insight regarding significant progress in ADRD biomarker research over the last decade, addresses potential challenges in the .