Guys who lost weight arent suddenly dating models, Women aren't suddenly happy to have smaller dress sizes. There isn't a sudden acceptance into social circles after this rapid weight loss change. This leads to a feeling of defeat. . Medicines and supplements can enhance your weight loss Some people use medications and miracle supplements to allow them to not notice hunger but eat less. I get asked at least times a month by patients and friends to give them phentermine. Nobody I know who has used phentermine has had a sustained weight loss, they haven't lost large amounts of weight, and the risks of the medication are great for people who already have enlarged hearts or elevated blood pressures.